365bet亚洲官方投注

教授/研究员
您的当前位置:首页  师资队伍  员工名录  教授/研究员
王峰
发布时间:2018-09-11    阅读次数: 4103

姓 名:
王峰
职 称:
教授,博士生导师
个人主页
http://wangf.hfut.edu.cn/ 
所属系:
食品质量与安全系
邮 箱:
fengw420@hfut.edu.cn ;fengw420@gmail.com
电 话:
18655108700
个人学习工作简介

        王峰博士2007年毕业于合肥工业大学,获得学士学位;2012年毕业于中国科学技术大学合肥微尺度物质科学国家实验室(筹),获得博士学位,导师为王均教授。博士毕业后在加拿大滑铁卢大学(University of Waterloo2012.11-2016.1, 2016.4-2016.10)化学系及纳米技术研究所从事博士后研究,导师为Juewen Liu(刘珏文)教授。2016年入选合肥工业大学“黄山青年学者”人才引进计划(教授,博士生导师)。王峰博士近年来一直致力于利用分析化学的手段研究纳米-生物界面的工作,在纳米材料与脂质体、细胞膜、核酸、免疫屏障的相互作用等领域取得了丰硕的研究成果。迄今,已在国际学术期刊J. Am. Chem. Soc.Angew.Chem. Int. Ed.Adv. Mater.Nano Lett.ACS NanoSmallBiomaterialsChem. Commun.NanoscaleAnal. Chem.等发表42篇学术论文。其中,以第一、共同第一和通讯作者身份在Adv. Mater.1篇),ACS Nano2篇),J. Am. Chem. Soc.1篇),Angew. Chem. Int. Ed.1篇),Small2篇),ACS Appl. Mater. Interfaces1篇),Nanoscale4篇),Chem. Commun.1篇),Anal. Chem.1篇)等国际期刊上发表22篇学术论文(IF 5-1010篇,IF>107篇);申请中国发明专利1项。迄今所有论文共被引2097次。多篇学术论文入选国际学术期刊的most-accessed article4篇论文引用超过100次(单篇最高引次566),H因子为23。目前承担基金包括国家自然科学基金面上项目两项(在研)、青年基金一项(已结题)、安徽省自然基金等。

主要研究领域与方向

主要研究方向集中在纳米-生物界面,包括:

1)纳米材料与细胞膜相互作用的调控及其在药物(基因)传递中的应用;

2)高效低毒抗肿瘤纳米药物的研制及其作用机制的研究;

3)纳米材料的毒理学评价;

4)纳米材料的光、电、磁性能调控和纳米催化效应等
代表性研究成果

工作一:系统地研究了无机纳米材料与脂质体的相互作用及其在药物传递中的应用。(Adv. Mater., 2013, 25, 4087; Nanoscale, 2013, 5, 12375; J. Am. Chem. Soc., 2015, 137, 11736; Angew. Chem. Int. Ed., 2016, 55, 12063; Nanoscale, 2015, 7, 15599; Nanoscale, 2015, 7, 15599; ACS Appl. Mater. Interfaces, 2017, 9, 17736; Langmuir, 2015, 31, 13271; Langmuir, 2018, 34, 6628; Langmuir, 2018, 34, 9937;Langmuir, 2019, 35, 1672ACS Nano, 2019, 13, 11967

工作二:构建了对肿瘤细胞内微环境响应的纳米药物载体系统,用于克服肿瘤细胞的耐药性。(ACS Nano, 2011, 5, 3679Bioconjugate Chem., 2011, 22, 1939

工作三:构筑核酸/核酸碱基为配体的金属配合物及其在分子识别等方面的应用。(Chem. Commun., 2013, 49, 9482Nanoscale, 2014, 6, 7079Anal. Chem., 2013, 85, 12144Biosens. Bioelectron., 2019, 142, 111531

工作四:系统地研究了纳米颗粒对雄性ICR小鼠的生殖毒性。(Small, 2013, 9, 1708Nano Lett., 2013, 13, 2477
目前承担科研项目

国家自然科学基金“面上项目”,亲水头部反转脂质与生物-纳米界面作用过程的机制、调控及生物医学应用,3197131420201月~202312月,主持

国家自然科学基金“面上项目”,纳米材料对脂质体相行为和流动性影响的基础研究,3157102320161月~201912月,主持

国家自然科学基金“青年科学基金项目”DNA在脂质体、纳米金表面杂交动力学的研究及生物应用,8150158720161月~201812月,主持

安徽省自然科学基金“杰青项目”20187月~20216月,主持

合肥工业大学“黄山青年学者”启动基金20161月~201812月,主持

合肥工业大学优秀青年人才培育A计划JZ2017HGPA016420174月~201912月,主持

安徽农业大学茶学国家重点实验室开放基金,单壁碳纳米管介导的茶树基因转化技术体系创制,SKLTOF20190111201911月~202110月,主持

广东省生物医学工程重点实验室开放课题基金20171月~201912月,主持

广东省自然科学基金“面上项目”,脂质支撑双层膜包被磁性纳米颗粒用于克服鼻咽癌耐药性的研究,201910月~202209月,参与
获奖情况
美国通用电器(GE)基金会科技创新一等奖(2011
发表的论文、专利与著作(代表作)

[1] Y. C. Ma, Y. X. Zhang, X. Q. Li, Y. Y. Zhao, M. Li, W. Jiang, X. F. Tang, J. X. Dou, L. G. Lu, F. Wang*, and Y. C. Wang*, Near-infrared II phototherapy induces deep tissue immunogenic cell death and potentiates cancer immunotherapy. ACS Nano, 2019, 13, 11967-11980

[2] H. Wang, H. Li, Y. Huang, M. H. Xiong, F. Wang*, C. Li*, A label-free electrochemical biosensor for highly sensitive detection of gliotoxin based on DNA nanostructure/MXene nanocomplexes. Biosensors and Bioelectronics, 2019, 142, 111531

[3] X. S. Wang, X. Q. Li, H. Wang, X. H. Zhang, L. Zhang, F. Wang* and J. W. Liu*, Charge and Coordination Directed Liposome Fusion onto SiO2 and TiO2 Nanoparticles. Langmuir, 2019, 35, 1672-1681 IF: 3.789

[4] X. R. Liu, X. Q. Li, W. Xu, X. H. Zhang, Z. C. Huang, F. Wang*, and J. W. Liu*, Sub-Angstrom Gold Nanoparticle/Liposome Interfaces Controlled by Halides. Langmuir, 2018, 34, 6628-6635 IF: 3.789

[5] Y. B. Li, F. Wang* and J. Liu*, Headgroup inversed liposomes: biointerfaces, supported bilayers and applications. Langmuir, 2018, 34, 9337-9348 IF: 3.789

[6] S. Y. Li, F. Wang*, X. Q. Li, J. Chen, X. H. Zhang, Y. C. Wang* and J. W. Liu*, Dipole Orientation Matters: Longer-Circulating Choline Phosphate than Phosphocholine Liposomes for Enhanced Tumor Targeting. ACS Applied Materials & Interfaces, 2017, 9, 17736-17744 IF: 8.097

[7] F. Wang, X. H. Zhang, Y. B. Liu, Z. Y. Lin, B. W. Liu and J. W. Liu*, Profiling metal oxides with lipids: Magnetic liposomal nanoparticles displaying DNA and proteins. Angewandte Chemie International Edition, 2016, 55, 12063-12067 IF: 12.102

[8] F. Wang, D. Curry and J. W. Liu*, Driving adsorbed gold nanoparticle assembly by merging lipid gel/fluid interfaces. Langmuir, 2015, 31, 13271-13274 IF: 3.789

[9] F. Wang and J. W. Liu*, A stable lipid/TiO2 interface with headgroup inversed phosphocholine and a comparison with SiO2. Journal of the American Chemical Society, 2015, 137, 11736-11742 IF: 14.357

[10] F. Wang and J. W. Liu*, Self-healable and reversible liposome leakage by citrate-capped gold nanoparticles probing initial adsorption/desorption induced lipid phase transition. Nanoscale, 2015, 7, 15599-15604 IF: 7.233

[11] F. Wang and J. W. Liu*, Evaporation induced wrinkling of graphene oxide at the nanoparticle interface. Nanoscale, 2015, 7, 919-923 IF: 7.233

[12] F. Wang and J. W. Liu*, Liposome supported metal oxide nanoparticles: interaction mechanism, light controlled content release and intracellular delivery. Small, 2014, 10, 3927-3931 IF: 9.598

[13] F. Wang and J. W. Liu*, Platinated DNA oligonucleotides: new probes forming ultrastable conjugates with graphene oxide. Nanoscale, 2014, 6, 7079-7084 IF: 7.233

[14] F. Wang, B. W. Liu, P. J. J. Huang and J. W. Liu*, Rationally designed nucleobase and nucleotide coordinated nanoparticles for selective DNA adsorption and detection. Analytical Chemistry, 2013, 85, 12144-12151 IF: 6.042

[15] F. Wang, B. W. Liu, A. C. F. Ip and J. W. Liu*, Orthogonal adsorption onto nano-graphene oxide using different intermolecular forces for multiplexed delivery. Advanced Materials, 2013, 25, 4087-4092 IF: 21.950

[16] F. Wang, P. J. J. Huang and J. W. Liu*, Citrate inhibition of cisplatin reaction with DNA studied using fluorescently labeled oligonucleotides: implication for selectivity towards guanine. Chemical Communications, 2013, 49, 9482-9484 IF: 6.290

[17] F. Wang and J. W. Liu*, Nanodiamond decorated liposomes as highly biocompatible delivery vehicles and a comparison with carbon nanotube and graphene oxide. Nanoscale, 2013, 5, 12375-12382 IF: 7.233

[18] W. Q. Li, F. Wang, Z. M. Liu, Y. C. Wang, J. Wang* and F. Sun*, Gold nanoparticles elevate plasma testosterone levels in male mice without affecting fertility. Small, 2013, 9, 1708-1714 IF: 9.598

[19] F. Wang, Y. C. Wang, S. Dou, M. H. Xiong, T. M. Sun and J. Wang*, Doxorubicin-tethered responsive gold nanoparticles facilitate intracellular drug delivery for overcoming multidrug resistance in cancer cells. ACS Nano, 2011, 5, 3679-3692 IF: 13.709

[20] F. Wang, R. Saran and J. W. Liu*, Tandem DNAzymes for mRNA cleavage: choice of enzyme, metal ions and the antisense effect. Bioorganic & Medicinal Chemistry Letters, 2015, 25, 1460-1463 IF: 2.442

[21] Y. C. Wang, F. Wang, T. M. Sun and J. Wang*, Redox-responsive nanoparticles from the single disulfide bond-bridged block copolymer as drug carriers for overcoming multidrug resistance in cancer cells. Bioconjugate Chemistry, 2011, 22, 1939-1945 IF: 4.485

[22] F. Wang, Y. C. Wang, L. F. Yan and J. Wang*, Biodegradable vesicular nanocarriers based on poly(ε-caprolactone)-block-poly(ethyl ethylene phosphate) for drug delivery. Polymer, 2009, 50, 5048-5054 IF: 3.483
其他情况

欢迎具有化学、物理、生物、药学、医学、食品等背景的学生报考实验室研究生;

欢迎对科研有兴趣的本科生来实验室,参与课题;

有意向从事博士后研究的科研工作者,请直接与王峰教授邮件联系
版权所有:365bet亚洲官方投注  技术支持:南京苏迪
地址:安徽省合肥市经济技术开发区大学城翡翠路420号  邮编:230601  电话:0551-62901285  邮箱:spxy@hfut.edu.cn
皖ICP备12146036号-1  您是本站第
访客!
触碰右侧展开